2021 Mercedes-Benz GLS vs 2022 Toyota Sequoia
Overview | |
MSRP$76,000 | MSRP$50,500 |
Listings152 | Listings36 |
Ratings & Reviews | |
User Reviews | User Reviews |
Expert reviews8.3 out of 10 | Expert reviews7.3 out of 10 |
Pros
Cons
| Pros
Cons
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2021 Mercedes-Benz GLS Reviews SummaryThe “S” in the 2021 Mercedes-Benz GLS-Class name is meant to connect the SUV to the S-Class flagship sedan. In this sense, the GLS is the S-Class of SUVs, and it delivers on that positioning. The 2021 GLS-Class has three rows of spacious seating, and puts comfort above all else. The GLS can hold groceries, weekend bags, antique desks purchased from a roadside consignment shop—all things that would require a lot of negotiating in the S-Class sedan. The GLS-Class is one member of a growing fraternity of full-size, three-row, luxury SUVs. Their ranks include the Cadillac Escalade, Lincoln Navigator, Infiniti QX80, and the more recent BMW X7. The GLS sets itself apart with a higher standard of luxury, and impressive performance… if you’re willing to shell out the cash. | |
2022 Toyota Sequoia Reviews SummaryThe 2022 Toyota Sequoia shares its platform with the Toyota Tundra pickup truck. It comes with rear-wheel-drive (RWD) or available four-wheel-drive (4WD) drivetrains, except TRD Pro models, which come with standard 4WD. The Sequoia and comes in six trim levels: SR5, TRD Sport, TRD Pro, Limited, Platinum, and the Nightshade Special Edition. While competitors have refreshed their full-size SUVs over the past few years, Toyota has stood pat with the Sequoia, relying on minor cosmetic updates to keep the SUV in the hunt since 2008. | |
No video found | No video found |
Popular Features & Specs | |
Engine3.0L 362 hp I6 | Engine5.7L 381 hp V8 |
Drive TrainAWD | Drive Train4X2 |
Seating Capacity7 | Seating Capacity8 |
Horsepower362 hp @ 5500 rpm | Horsepower381 hp @ 5600 rpm |
MPG City20 | MPG City13 |
MPG Highway24 | MPG Highway17 |
Engine | |
Engine Name3.0L 362 hp I6 | Engine Name5.7L 381 hp V8 |
Torque369 lb-ft @ 1600 rpm | Torque401 lb-ft @ 3600 rpm |
Horsepower362 hp @ 5500 rpm | Horsepower381 hp @ 5600 rpm |
DrivetrainAWD | Drivetrain4X2 |
Fuel Economy | |
MPG City20 | MPG City13 |
MPG Highway24 | MPG Highway17 |
Interior | |
Seating Capacity7 | Seating Capacity8 |
Key Features | |
Navigation SystemStandard | Navigation System |
Sunroof/MoonroofStandard | Sunroof/MoonroofStandard |
Dimensions & Capacity | |
Cargo Space17.4 cu ft | Cargo Space18.9 cu ft |
Curb Weight5467 lbs | Curb Weight5730 lbs |
Height72.4 in | Height77.0 in |
Length205.0 in | Length205.1 in |
Width84.9 in | Width79.9 in |
Wheelbase123.4 in | Wheelbase122.0 in |
Maximum Payload1808 lbs | Maximum Payload1405 lbs |
Number of doors4 | Number of doors4 |
Maximum Towing Capacity7700 lbs | Maximum Towing Capacity7400 lbs |
Standard Towing Capacity | Standard Towing Capacity7400 lbs |
Overview | ||
MSRP | $76,000 | $50,500 |
Listings | ||
Ratings & Reviews | ||
User reviews | ||
Expert reviews | 8.3 out of 10Read full review | 7.3 out of 10Read full review |
Pros & cons | Pros
Cons
| Pros
Cons
|
Summary | The “S” in the 2021 Mercedes-Benz GLS-Class name is meant to connect the SUV to the S-Class flagship sedan. In this sense, the GLS is the S-Class of SUVs, and it delivers on that positioning. The 2021 GLS-Class has three rows of spacious seating, and puts comfort above all else. The GLS can hold groceries, weekend bags, antique desks purchased from a roadside consignment shop—all things that would require a lot of negotiating in the S-Class sedan. The GLS-Class is one member of a growing fraternity of full-size, three-row, luxury SUVs. Their ranks include the Cadillac Escalade, Lincoln Navigator, Infiniti QX80, and the more recent BMW X7. The GLS sets itself apart with a higher standard of luxury, and impressive performance… if you’re willing to shell out the cash. | The 2022 Toyota Sequoia shares its platform with the Toyota Tundra pickup truck. It comes with rear-wheel-drive (RWD) or available four-wheel-drive (4WD) drivetrains, except TRD Pro models, which come with standard 4WD. The Sequoia and comes in six trim levels: SR5, TRD Sport, TRD Pro, Limited, Platinum, and the Nightshade Special Edition. While competitors have refreshed their full-size SUVs over the past few years, Toyota has stood pat with the Sequoia, relying on minor cosmetic updates to keep the SUV in the hunt since 2008. |
Video | No video found | No video found |
Popular Features & Specs | ||
Engine | 3.0L 362 hp I6 | 5.7L 381 hp V8 |
Drive Train | AWD | 4X2 |
Seating Capacity | 7 | 8 |
Horsepower | 362 hp @ 5500 rpm | 381 hp @ 5600 rpm |
MPG City | 20 | 13 |
MPG Highway | 24 | 17 |
Engine | ||
Engine Name | 3.0L 362 hp I6 | 5.7L 381 hp V8 |
Torque | 369 lb-ft @ 1600 rpm | 401 lb-ft @ 3600 rpm |
Horsepower | 362 hp @ 5500 rpm | 381 hp @ 5600 rpm |
Drivetrain | AWD | 4X2 |
Fuel Economy | ||
MPG City | 20 | 13 |
MPG Highway | 24 | 17 |
Interior | ||
Seating Capacity | 7 | 8 |
Key Features | ||
Navigation System | Standard | |
Sunroof/Moonroof | Standard | Standard |
Dimensions & Capacity | ||
Cargo Space | 17.4 cu ft | 18.9 cu ft |
Curb Weight | 5467 lbs | 5730 lbs |
Height | 72.4 in | 77.0 in |
Length | 205.0 in | 205.1 in |
Width | 84.9 in | 79.9 in |
Wheelbase | 123.4 in | 122.0 in |
Maximum Payload | 1808 lbs | 1405 lbs |
Number of doors | 4 | 4 |
Maximum Towing Capacity | 7700 lbs | 7400 lbs |
Standard Towing Capacity | 7400 lbs | |
The 2021 Mercedes-Benz GLS, a continuation of the third generation introduced in 2020, was a luxurious SUV that offered a blend of style and practicality. Originally launched as the GL-Class in 2006, it was intended to replace the G-Class but instead found its niche among affluent families seeking a more comfortable alternative to the Navigator and Escalade. The GLS featured a sleek design with softened angles and a futuristic interior dominated by a massive digital screen, emphasizing its tech-reliant nature. Available in three trims—GLS 450, GLS 580, and the high-performance AMG GLS 63—the GLS offered a range of standard features, including remote keyless entry, nine USB ports, and a 13-speaker Burmester sound system. Optional packages allowed for further customization, adding features like ventilated seats and rear-seat controls.
In contrast, the 2022 Toyota Sequoia, a model that had not seen a complete redesign since 2008, maintained a classic and mature design. Despite its age, the Sequoia's exterior remained tasteful, with modestly sized grilles and elegant wheel arches. Its substantial dimensions and ground clearance made it a commanding presence on the road. Inside, the Sequoia's design felt dated compared to modern SUVs, with a smaller 7-inch touchscreen and a 4.5-inch driver information screen. However, the interior was built to last, with high-quality materials and a focus on durability. The Nightshade Special Edition added a contemporary touch with darkened chrome and black-painted finishes, enhancing its visual appeal.















The 2021 Mercedes-Benz GLS offered a range of powerful engines, starting with the GLS 450's twin-turbocharged 3.0-liter inline-six engine, producing 362 horsepower and 369 pound-feet of torque. The GLS 580 upgraded to a twin-turbocharged 4.0-liter V8, delivering 483 hp and 516 lb-ft. The AMG GLS 63, with its hand-crafted 4.0-liter twin-turbo V8, boasted an impressive 603 hp and 627 lb-ft of torque. All engines featured Mercedes' EQ Boost 48-volt mild-hybrid system, adding extra power when needed. The AMG GLS 63 could accelerate from zero to 60 mph in just 4.1 seconds, with a top speed of 174 mph. Its adaptive air suspension and multiple drive modes provided a smooth and agile driving experience, even on challenging roads.
The 2022 Toyota Sequoia, on the other hand, relied on a single powertrain option: the 5.7-liter i-Force V8 engine, producing 381 horsepower and 401 pound-feet of torque. Paired with a six-speed automatic transmission, the Sequoia offered a reliable and durable performance. With a payload capacity of around 1,300 pounds and a towing capacity of 7,400 pounds, it was well-suited for heavy-duty tasks. However, its fuel economy lagged behind modern standards, with ratings of 13 mpg city/17 mpg highway for both RWD and 4WD models. Despite its weight, the Sequoia provided a stable and comfortable ride, with excellent off-road capabilities thanks to its robust construction and independent suspension.
The 2021 Mercedes-Benz GLS excelled in providing spacious and comfortable seating across its three rows. With standard seven-passenger seating, optional second-row captain's chairs reduced capacity to six. The front and second-row passengers enjoyed ample headroom and legroom, while the third row accommodated full-size adults comfortably. The GLS offered 17.4 cubic feet of cargo space behind the third row, expanding to 42.7 cubic feet with the third row folded. With all seats down, it provided 87.4 cubic feet of cargo space. The interior featured numerous storage compartments, including spacious in-door bins and a center console with butterfly doors.
The 2022 Toyota Sequoia prioritized passenger comfort, offering roomy seating across all three rows. Three-zone climate control catered to all occupants, and a standard power moonroof added to the airy feel. The Sequoia's cargo compartment featured an auxiliary 12-volt outlet, ideal for outdoor activities. With 18.9 cubic feet of space behind the third row, folding the seats expanded cargo capacity to 66.6 cubic feet. With both rows folded flat, the Sequoia offered an impressive 120.1 cubic feet of space, making it a practical choice for families and adventurers alike.
The 2021 Mercedes-Benz GLS featured the advanced MBUX infotainment system, with a large touch screen and a trackpad for easy navigation. It included Apple CarPlay and Android Auto, though a USB-C cable was required for connectivity. The MBUX system's voice control allowed for complex commands, enhancing convenience. The digital dash extended to the fully-digital instrument panel, controlled by touch-sensitive pads on the steering wheel. While there was a learning curve, the system offered a seamless integration of technology.
In contrast, the 2022 Toyota Sequoia's infotainment system felt outdated, with a 7-inch touchscreen and a clunky operating system. Apple CarPlay and Android Auto were standard, providing some modern connectivity. The Sequoia Limited added navigation and a 12-speaker audio system, with an optional premium audio package. While the Sequoia lacked advanced powertrain technology, it featured LED lighting and a rear backup camera, with upper trims offering a power liftgate.
The 2021 Mercedes-Benz GLS came equipped with a comprehensive suite of driver-assistance features, including Active Brake Assist, forward-collision avoidance, and blind-spot monitoring. Additional safety tech included lane-keep assist, adaptive cruise control, and a following-distance indicator. The GLS also featured a full array of airbags, traction control, and a tire-pressure monitoring system.
The 2022 Toyota Sequoia, while lacking crash-test ratings, offered the Toyota Safety Sense P suite, including pre-collision system with pedestrian detection, adaptive cruise control, and lane-departure alert. Standard blind-spot monitoring and rear cross-traffic alert enhanced safety. The Sequoia also featured Toyota's STAR safety system, with stability control, traction control, and a full complement of airbags.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Mercedes-Benz GLS is 8.3 out of 10, while the 2022 Toyota Sequoia scores 7.3 out of 10. Based on these ratings, the Mercedes-Benz GLS is the recommended choice for those seeking a more refined and technologically advanced SUV.
Choose the 2021 Mercedes-Benz GLS if:
- You prioritize advanced technology and a luxurious interior.
- You seek powerful engine options and impressive performance.
- You value a comprehensive suite of safety features.
Choose the 2022 Toyota Sequoia if:
- You need a spacious and durable SUV for family adventures.
- You require substantial towing and payload capacities.
- You prefer a straightforward and reliable powertrain.
CarGurus highlights

According to CarGurus experts, the overall rating for the 2021 Mercedes-Benz GLS is 8.3 out of 10, while the 2022 Toyota Sequoia scores 7.3 out of 10. Based on these ratings, the Mercedes-Benz GLS is the recommended choice for those seeking a more refined and technologically advanced SUV.
Choose the 2021 Mercedes-Benz GLS if:
Shop Now- You prioritize advanced technology and a luxurious interior.
- You seek powerful engine options and impressive performance.
- You value a comprehensive suite of safety features.
Choose the 2022 Toyota Sequoia if:
Shop Now- You need a spacious and durable SUV for family adventures.
- You require substantial towing and payload capacities.
- You prefer a straightforward and reliable powertrain.

By: CarGurus + AI
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