CarGurus Header

2021 Mercedes-Benz GLS vs 2021 Toyota Highlander Hybrid

2021 Mercedes-Benz GLS
2021 Mercedes-Benz GLS
$76,000MSRP
Overview
Overview
OverviewShop Now
2021 Toyota Highlander Hybrid
2021 Toyota Highlander Hybrid
$38,735MSRP
Overview
Overview
OverviewShop Now
2021 Mercedes-Benz GLS
$76,000MSRP
Overview
Overview
OverviewShop Now
2021 Toyota Highlander Hybrid
$38,735MSRP
Overview
Overview
OverviewShop Now

Overview

MSRP

$76,000

MSRP

$38,735

Listings

152

Listings

54

Ratings & Reviews

User Reviews
User Reviews

Expert reviews

8.3 out of 10

Expert reviews

6.7 out of 10

Pros

  • Multiple powertrain options

  • Plenty of cargo space

  • Impressive technology

Cons

  • Cramped third row

  • Unintuitive technology

  • Poor fuel economy

Pros

  • Spacious

  • Excellent value for money

  • Fuel-efficient

Cons

  • Uninspired styling

  • Cramped third row

  • Outdated technology

2021 Mercedes-Benz GLS Reviews Summary

The “S” in the 2021 Mercedes-Benz GLS-Class name is meant to connect the SUV to the S-Class flagship sedan. In this sense, the GLS is the S-Class of SUVs, and it delivers on that positioning. The 2021 GLS-Class has three rows of spacious seating, and puts comfort above all else. The GLS can hold groceries, weekend bags, antique desks purchased from a roadside consignment shop—all things that would require a lot of negotiating in the S-Class sedan.

The GLS-Class is one member of a growing fraternity of full-size, three-row, luxury SUVs. Their ranks include the Cadillac Escalade, Lincoln Navigator, Infiniti QX80, and the more recent BMW X7. The GLS sets itself apart with a higher standard of luxury, and impressive performance… if you’re willing to shell out the cash.

2021 Toyota Highlander Hybrid Reviews Summary

There comes a time in everyone’s life when practicality rules. Usually, it arrives shortly before or after having children. In many ways, the 2021 Toyota Highlander is purpose-built to provide that practicality—especially in hybrid form. Redesigned for the 2020 model year, the 2021 Highlander adds a sporty XSE trim level (V6 models only), improved headlights on lower trim levels, and an upgraded Toyota Safety Sense 2.5+ collection of safety features. These changes can only make the Highlander a more appealing choice in a highly competitive segment.
No video found
No video found

Popular Features & Specs

Engine

3.0L 362 hp I6

Engine

2.5L 243 hp I4 Hybrid

Drive Train

AWD

Drive Train

FWD

Seating Capacity

7

Seating Capacity

8

Horsepower

362 hp @ 5500 rpm

Horsepower

EV Battery Capacity

EV Battery Capacity

1.9 kWh

MPG City

20

MPG City

36

MPG Highway

24

MPG Highway

35
2021 Mercedes-Benz GLS
2021 Mercedes-Benz GLS
$76,000MSRP
Overview
Overview
OverviewShop Now
2021 Toyota Highlander Hybrid
2021 Toyota Highlander Hybrid
$38,735MSRP
Overview
Overview
OverviewShop Now
2021 Mercedes-Benz GLS
$76,000MSRP
Overview
Overview
OverviewShop Now
2021 Toyota Highlander Hybrid
$38,735MSRP
Overview
Overview
OverviewShop Now

Overview

MSRP
$76,000
$38,735
Listings

Ratings & Reviews

User reviews

4.7

4.9

Expert reviews

8.3 out of 10

Read full review

6.7 out of 10

Read full review
Pros & cons

Pros

  • Multiple powertrain options

  • Plenty of cargo space

  • Impressive technology

Cons

  • Cramped third row

  • Unintuitive technology

  • Poor fuel economy

Pros

  • Spacious

  • Excellent value for money

  • Fuel-efficient

Cons

  • Uninspired styling

  • Cramped third row

  • Outdated technology

Summary

The “S” in the 2021 Mercedes-Benz GLS-Class name is meant to connect the SUV to the S-Class flagship sedan. In this sense, the GLS is the S-Class of SUVs, and it delivers on that positioning. The 2021 GLS-Class has three rows of spacious seating, and puts comfort above all else. The GLS can hold groceries, weekend bags, antique desks purchased from a roadside consignment shop—all things that would require a lot of negotiating in the S-Class sedan.

The GLS-Class is one member of a growing fraternity of full-size, three-row, luxury SUVs. Their ranks include the Cadillac Escalade, Lincoln Navigator, Infiniti QX80, and the more recent BMW X7. The GLS sets itself apart with a higher standard of luxury, and impressive performance… if you’re willing to shell out the cash.

There comes a time in everyone’s life when practicality rules. Usually, it arrives shortly before or after having children. In many ways, the 2021 Toyota Highlander is purpose-built to provide that practicality—especially in hybrid form. Redesigned for the 2020 model year, the 2021 Highlander adds a sporty XSE trim level (V6 models only), improved headlights on lower trim levels, and an upgraded Toyota Safety Sense 2.5+ collection of safety features. These changes can only make the Highlander a more appealing choice in a highly competitive segment.
Video
No video found
No video found

Popular Features & Specs

Engine
3.0L 362 hp I6
2.5L 243 hp I4 Hybrid
Drive Train
AWD
FWD
Seating Capacity
7
8
Horsepower
362 hp @ 5500 rpm
EV Battery Capacity
1.9 kWh
MPG City
20
36
MPG Highway
24
35
Look and feel

2021 Mercedes-Benz GLS

9/10

2021 Toyota Highlander Hybrid

7/10

The 2021 Mercedes-Benz GLS, a continuation of the third generation introduced in 2020, evolved from the GL-Class, which debuted in 2006. Initially intended to replace the G-Class, the GLS instead attracted a different clientele, offering a luxurious, family-friendly alternative to the Navigator and Escalade. The GLS featured a more refined design with softened angles and a futuristic interior highlighted by a massive digital screen. Available in three trims—GLS 450, GLS 580, and AMG GLS 63—the GLS offered a range of standard features, including remote start, nine USB ports, and a premium sound system. The AMG GLS 63 stood out with aggressive styling and performance-inspired interior elements.

The 2021 Toyota Highlander Hybrid presented a bold design with a distinctive front end and floating roof appearance. Despite its polarizing look, the Highlander aimed to remain recognizable on the road. Offered in LE, XLE, Limited, and Platinum trims, the Highlander Hybrid featured a hybrid powertrain option, enhancing fuel efficiency. The Limited trim, evaluated in this review, included a 12.3-inch touchscreen, electronic all-wheel drive, and leather upholstery. While the interior offered upscale touches, some details, like the instrument-panel shroud, felt less refined. The Highlander Hybrid's design and features aimed to balance style with practicality.

Picture of 2021 Mercedes-Benz GLS
Picture of 2021 Mercedes-Benz GLS
Picture of 2021 Mercedes-Benz GLS
Picture of 2021 Mercedes-Benz GLS
Picture of 2021 Mercedes-Benz GLS
Picture of 2021 Mercedes-Benz GLS
Picture of 2021 Mercedes-Benz GLS
Picture of 2021 Mercedes-Benz GLS
Picture of 2021 Mercedes-Benz GLS
Performance

2021 Mercedes-Benz GLS

9/10

2021 Toyota Highlander Hybrid

4/10

The 2021 Mercedes-Benz GLS offered a range of powerful engines. The GLS 450 featured a 3.0-liter inline-six engine producing 362 horsepower, while the GLS 580 boasted a 4.0-liter V8 with 483 hp. The AMG GLS 63, with its hand-crafted 4.0-liter twin-turbo V8, delivered an impressive 603 hp. All models included Mercedes’ EQ Boost system, adding extra power when needed. The AMG GLS 63 accelerated from 0 to 60 mph in just 4.1 seconds, showcasing remarkable performance for its size. The GLS also featured an adaptive air suspension system, enhancing its handling and ride comfort.

The 2021 Toyota Highlander Hybrid transitioned to a 2.5-liter four-cylinder engine, achieving 36 mpg in combined driving. With a total output of 243 hp, the Highlander Hybrid prioritized efficiency over performance. While it managed hills and freeway speeds, the engine sounded strained under pressure. The steering felt lifeless, but the regenerative brakes performed well. The Highlander Hybrid excelled in fuel economy, though it lacked the driving excitement of its predecessor. Its ride comfort was suitable for smooth roads, but it struggled with more challenging terrain.

Form and function

2021 Mercedes-Benz GLS

8/10

2021 Toyota Highlander Hybrid

5/10

The 2021 Mercedes-Benz GLS provided spacious seating across three rows, accommodating up to seven passengers. The front and second rows offered ample space, while the third row was suitable for adults. The GLS boasted 17.4 cubic feet of cargo space behind the third row, expanding to 87.4 cubic feet with seats folded. The interior featured numerous storage compartments, enhancing practicality.

The 2021 Toyota Highlander Hybrid offered comfortable seating for the driver and front passenger, with adjustable power seats and leather upholstery. The second-row bench seat increased capacity to eight but felt cramped for three adults. The third row was less comfortable, with limited legroom and headroom. Cargo space measured 16 cubic feet behind the third row, expanding to 84.3 cubic feet with seats folded. Storage options were adequate but less generous than previous models.

Technology

2021 Mercedes-Benz GLS

9/10

2021 Toyota Highlander Hybrid

8/10

The 2021 Mercedes-Benz GLS featured the MBUX infotainment system with a large touchscreen and voice-control capabilities. It included Apple CarPlay and Android Auto, though required a USB-C connection. The digital dash extended to the instrument panel, offering customizable displays. The system's learning curve was offset by its comprehensive functionality.

The 2021 Toyota Highlander Hybrid came equipped with Bluetooth, Apple CarPlay, Android Auto, and Amazon Alexa. The Limited trim featured a 12.3-inch touchscreen and JBL audio system. The infotainment system was user-friendly, with large controls and effective voice recognition. Additional features included Driver Easy Speak and a video rearview mirror, enhancing convenience and safety.

Safety

2021 Mercedes-Benz GLS

9/10

2021 Toyota Highlander Hybrid

8/10

The 2021 Mercedes-Benz GLS included standard driver-assistance features like Active Brake Assist, blind-spot monitoring, and a surround-view camera. Optional safety tech included lane-keep assist and adaptive cruise control. The GLS provided comprehensive safety equipment, ensuring a secure driving experience.

The 2021 Toyota Highlander Hybrid featured Toyota Safety Sense 2.5+, offering advanced driver-assist technologies. While blind-spot monitoring required an upgrade, the system effectively supported safe driving. The Highlander received a five-star overall rating from NHTSA and was expected to achieve a "Top Safety Pick+" from IIHS.

Cost Effectiveness

2021 Mercedes-Benz GLS

6/10

2021 Toyota Highlander Hybrid

8/10
N/A

CarGurus highlights

Winning Vehicle Image

According to CarGurus experts, the overall rating for the 2021 Mercedes-Benz GLS is 8.3 out of 10, while the 2021 Toyota Highlander Hybrid scores 6.7 out of 10. Based on these ratings, the Mercedes-Benz GLS is the recommended choice for those seeking a luxurious and high-performing SUV.

Choose the 2021 Mercedes-Benz GLS if:

8.3of 10overall
  • You prioritize luxury and advanced technology features.
  • You desire powerful engine options and impressive performance.
  • You need spacious seating and cargo capacity for family trips.
152 results
See all

Choose the 2021 Toyota Highlander Hybrid if:

6.7of 10overall
  • You value fuel efficiency and eco-friendly driving.
  • You seek a practical and comfortable family SUV.
  • You appreciate user-friendly technology and safety features.
54 results
See all

CarGurus highlights

Winning Vehicle Image

According to CarGurus experts, the overall rating for the 2021 Mercedes-Benz GLS is 8.3 out of 10, while the 2021 Toyota Highlander Hybrid scores 6.7 out of 10. Based on these ratings, the Mercedes-Benz GLS is the recommended choice for those seeking a luxurious and high-performing SUV.

Choose the 2021 Mercedes-Benz GLS if:

Shop Now
8.3of 10overall
  • You prioritize luxury and advanced technology features.
  • You desire powerful engine options and impressive performance.
  • You need spacious seating and cargo capacity for family trips.
152 results

Choose the 2021 Toyota Highlander Hybrid if:

Shop Now
6.7of 10overall
  • You value fuel efficiency and eco-friendly driving.
  • You seek a practical and comfortable family SUV.
  • You appreciate user-friendly technology and safety features.
54 results

CarGurus logo

By: CarGurus + AI

At CarGurus, our team of experienced automotive writers remain at the heart of our content operation, conducting hands-on car tests and writing insightful guides that are backed by years of industry experience. To complement this, we are harnessing AI to make our content offering more diverse and more helpful to shoppers than ever. To achieve this, our AI systems are based exclusively on CarGurus content, ratings and data, so that what we produce is both unique to CarGurus, and uniquely helpful to car shoppers.

Popular vehicle comparisons

2023 Mercedes-Benz GLS vs 2024 Lexus RX Hybrid2023 Toyota Sequoia vs 2023 Mercedes-Benz GLS2023 Mercedes-Benz GLS vs 2024 MINI Countryman2023 Mercedes-Benz GLS vs 2023 Lexus NX2023 Mercedes-Benz GLS vs 2023 Volkswagen ID.42023 Mercedes-Benz GLS vs 2023 Lexus RX Hybrid2023 MINI Countryman vs 2023 Mercedes-Benz GLS2023 Mercedes-Benz GLS vs 2024 Toyota Sequoia2023 Mercedes-Benz GLS vs 2023 INFINITI QX802023 Mercedes-Benz GLS vs 2024 Lexus NX2023 Mercedes-Benz GLS vs 2024 INFINITI QX802022 Mercedes-Benz GLS vs 2023 Toyota Sequoia2022 Lexus NX vs 2022 Toyota Highlander Hybrid2022 Mercedes-Benz GLS vs 2023 Lexus NX2022 Lexus RX Hybrid vs 2023 Mercedes-Benz GLS2022 Mercedes-Benz GLS vs 2023 INFINITI QX802022 Mercedes-Benz GLS vs 2022 Land Rover Range Rover Velar2022 Toyota Highlander Hybrid vs 2023 Genesis GV802022 Toyota Highlander Hybrid vs 2023 Toyota Sequoia2022 Toyota Highlander Hybrid vs 2023 Toyota Sienna2022 Toyota Highlander Hybrid vs 2023 Kia Seltos2022 Toyota Sequoia vs 2023 Mercedes-Benz GLS2022 INFINITI QX80 vs 2023 Mercedes-Benz GLS2022 Toyota Highlander Hybrid vs 2023 Kia Sorento2022 Land Rover Range Rover Velar vs 2023 Mercedes-Benz GLS2021 Lexus RX Hybrid vs 2022 Mercedes-Benz GLS2021 Lexus NX vs 2022 Toyota Highlander Hybrid2021 Ford Explorer vs 2022 Toyota Highlander Hybrid2021 Chrysler Pacifica vs 2022 Toyota Highlander Hybrid2021 Toyota Highlander Hybrid vs 2022 Mercedes-Benz GLS2021 Kia Sorento vs 2022 Toyota Highlander Hybrid2021 Porsche Macan vs 2022 Toyota Highlander Hybrid2021 Lexus NX vs 2022 Mercedes-Benz GLS2021 Toyota Sequoia vs 2022 Mercedes-Benz GLS2021 Volkswagen ID.4 vs 2022 Mercedes-Benz GLS2021 MINI Countryman vs 2022 Mercedes-Benz GLS2021 Nissan Armada vs 2022 Toyota Highlander Hybrid2021 Toyota Sequoia vs 2022 Toyota Highlander Hybrid2020 Mercedes-Benz GLS vs 2020 MINI Countryman2020 Mercedes-Benz GLS vs 2021 Lexus RX Hybrid2020 Mercedes-Benz GLS vs 2020 Lexus RX Hybrid2020 Mercedes-Benz GLS vs 2021 INFINITI QX802020 Mercedes-Benz GLS vs 2021 Toyota Sequoia2020 Mercedes-Benz GLS vs 2020 INFINITI QX802020 Mercedes-Benz GLS vs 2020 Lexus NX2020 Mercedes-Benz GLS vs 2021 MINI Countryman2020 Land Rover Range Rover Velar vs 2020 Mercedes-Benz GLS2019 Mercedes-Benz GLS vs 2020 Lexus RX Hybrid2019 Mercedes-Benz GLS vs 2020 MINI Countryman2019 MINI Countryman vs 2019 Mercedes-Benz GLS2019 Lexus RX Hybrid vs 2020 Mercedes-Benz GLS2019 Mercedes-Benz GLS vs 2020 INFINITI QX802019 Mercedes-Benz GLS vs 2020 Lexus NX2019 INFINITI QX80 vs 2019 Mercedes-Benz GLS2019 INFINITI QX80 vs 2020 Mercedes-Benz GLS2019 Lexus NX vs 2020 Mercedes-Benz GLS2019 Lexus RX Hybrid vs 2019 Mercedes-Benz GLS
CarGurus Footer