Used 2021 Mercedes-Benz CLS for SaleNationwide
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 85,757
- Stock #:
- A-743
- VIN:
- W1K2J5JB7MA090983
2021 Mercedes-Benz CLS
450 RWD
85,757 mi
$30,145
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 43,415
- Stock #:
- A103866T
- VIN:
- W1K2J5KB4NA103866
-$1,210
2022 Mercedes-Benz CLS
450 4MATIC
43,415 mi
$37,592
$36,382
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Iridium Silver Metallic
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 96,397
- Stock #:
- LA048249
- VIN:
- WDD2J5JB2LA048249
-$1,000
2020 Mercedes-Benz CLS
450 Coupe RWD
96,397 mi
$24,460
$23,460
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Obsidian Black Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray (Macchiato/Magma Grey)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 21,291
- Stock #:
- NA101046
- VIN:
- W1K2J5KB0NA101046
2022 Mercedes-Benz CLS
450 4MATIC
21,291 mi
$47,494
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Leather Upholstery
- Transmission:
- 9-Speed Automatic
- Mileage:
- 53,067
- Stock #:
- 44816P
- VIN:
- W1K2J5JBXMA086636
2021 Mercedes-Benz CLS
450 RWD
53,067 mi
$36,067
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 20,692
- Stock #:
- PMDTLA074542
- VIN:
- W1K2J5KB0LA074542
2020 Mercedes-Benz CLS
450 Coupe 4MATIC
20,692 mi
$38,196
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Gray (Graphite Grey Metallic)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Red Stitching
- Transmission:
- 9-Speed Automatic
- Mileage:
- 32,862
- Stock #:
- N051042A
- VIN:
- WDD2J6BB0LA051042
2020 Mercedes-Benz CLS
AMG CLS 53 Coupe 4MATIC
32,862 mi
$44,199
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Graphite Gray Metallic
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 58,603
- Stock #:
- MA086615
- VIN:
- W1K2J5KB4MA086615
2021 Mercedes-Benz CLS
450 4MATIC
58,603 mi
$39,100
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 39,042
- Stock #:
- BW6641
- VIN:
- W1K2J5KB1NA104960
-$1,071
2022 Mercedes-Benz CLS
450 4MATIC
39,042 mi
$39,393
$38,322
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 82,399
- Stock #:
- PM5960
- VIN:
- W1K2J5JB0LA073831
2020 Mercedes-Benz CLS
450 Coupe RWD
82,399 mi
$26,369
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 68,746
- Stock #:
- CCJTLA050650
- VIN:
- WDD2J6BB7LA050650
2020 Mercedes-Benz CLS
AMG CLS 53 Coupe 4MATIC
68,746 mi
$34,986
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 48,332
- Stock #:
- 047844
- VIN:
- WDD2J5JB0LA047844
2020 Mercedes-Benz CLS
450 Coupe RWD
48,332 mi
$35,931
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- designo Diamond White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Magma Gray)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 34,019
- Stock #:
- 089725T
- VIN:
- W1K2J5JB2MA089725
2021 Mercedes-Benz CLS
450 RWD
34,019 mi
$40,817
About 2021 Mercedes-Benz CLS
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 17,888
- Stock #:
- 087842A
- VIN:
- W1K2J5JB7MA087842
2021 Mercedes-Benz CLS
450 RWD
17,888 mi
$45,487
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- 9-Speed Automatic
- Mileage:
- 71,183
- Stock #:
- LA049327
- VIN:
- WDD2J5JB1LA049327
2020 Mercedes-Benz CLS
450 Coupe RWD
71,183 mi
$30,395
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray (designo MANUFAKTUR Graphite Metallic)
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 49,710
- Stock #:
- 095079
- VIN:
- W1K2J5KB7MA095079
-$1,890
2021 Mercedes-Benz CLS
450 4MATIC
49,710 mi
$37,780
$35,890
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 47,637
- Stock #:
- A052426A
- VIN:
- WDD2J5KB9LA052426
2020 Mercedes-Benz CLS
450 Coupe 4MATIC
47,637 mi
$35,339
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray (Macchiato/Magma Grey)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 61,188
- Stock #:
- UMC7544
- VIN:
- WDD2J5JB4LA054215
-$1,795
2020 Mercedes-Benz CLS
450 Coupe RWD
61,188 mi
$31,890
$31,090
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Designo Diamond White Metallic
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 36,143
- Stock #:
- MA089756
- VIN:
- W1K2J5KB4MA089756
-$2,549
2021 Mercedes-Benz CLS
450 4MATIC
36,143 mi
$40,151
$37,602
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 58,657
- Stock #:
- 074781
- VIN:
- W1K2J5JB5LA074781
2020 Mercedes-Benz CLS
450 Coupe RWD
58,657 mi
$31,957
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- MANUFAKTUR Diamond White Bright
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Classic Red/Black
- Transmission:
- Automatic
- Mileage:
- 42,672
- Stock #:
- 108134
- VIN:
- W1K2J5KBXNA108134
2022 Mercedes-Benz CLS
450 4MATIC
42,672 mi
$39,990
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Graphite Gray Metallic
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- designo Black/Titanium Gray Pearl
- Transmission:
- 9-Speed Automatic
- Mileage:
- 89,284
- Stock #:
- TLA047828
- VIN:
- WDD2J5JB2LA047828
2020 Mercedes-Benz CLS
450 Coupe RWD
89,284 mi
$25,413
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 83,401
- Stock #:
- 049257
- VIN:
- WDD2J6BB0LA049257
2020 Mercedes-Benz CLS
AMG CLS 53 Coupe 4MATIC
83,401 mi
$34,575
Overview
The Mercedes-Benz CLS-Class is a large luxury car with coupe-like styling. It was last redesigned for the 2019 model year and gets updated tech features for 2021. It competes with cars like the Audi A7 and Genesis G90.
The CLS-Class is a big four-door car, though it’s graceful and elegant thanks to its low stance, sleek roofline, and blacked-out B-pillar for the the-oh-so-popular coupe-like profile. The wide grille and angled headlights make the front end look a little more sporty than you might expect based on the side view, and because it’s a Mercedes, the various wheel designs are gorgeous.
There are two CLS models, the CLS 450 and the AMG CLS 53, both carrying over unchanged this year. The CLS 450 features an inline-six engine rated for 362 horsepower and 369 pound-feet of torque, a nine-speed automatic transmission, and a mild-hybrid electrical system. Rear-wheel drive (RWD) is standard and Mercedes’ 4MATIC all-wheel drive (AWD) system is available. The AMG model is tuned for 429 hp and 384 lb-ft, and also features a (performance-enhanced) nine-speed transmission and AWD. With the base CLS, you’ll get 24 mpg city, 31 highway, and 26 combined, or 23/26/30 with AWD. The AMG CLS 53 is rated for 21/27/23.
The CLS seats five on leather upholstery and includes features like keyless entry, push-button start, and 64-color ambient lighting. The AMG model adds upgraded upholstery and a sport steering wheel. Options across the lineup include heated and cooled seats, massaging seats, and three-zone automatic climate control.
For 2021, the CLS gets an updated infotainment system in the form of the Mercedes-Benz User Experience (MBUX) system. A 12.3-inch display pairs with a new 12.3-inch digital gauge cluster for all functions, and Apple CarPlay and Android Auto are also included. The adaptive cruise control system now incorporates live traffic data—another nice touch. Buyers have the choice of two Burmester audio systems.
Standard safety features include blind-spot monitoring, forward-collision warning, automatic emergency braking, and driver-attention monitoring. For 2021, the automatic emergency braking system responds to oncoming traffic.
The lovely CLS-Class remains an enticing choice, and the updated tech features help it stay competitive.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Mercedes-Benz CLS Trims
| Trim type | MSRP |
|---|---|
| AMG CLS 53 4MATIC | $81,550 |
| 450 RWD | $70,300 |
| 450 4MATIC | $72,800 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Mercedes-Benz CLS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz CLS prices has changed over time.
See more price trends2021 Mercedes-Benz CLS Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest-Price Market: The Dallas, TX market leads with an average price of $47,288, indicating strong demand and possibly limited supply.
- Best Value: The Houston, TX market offers the lowest average price at $29,995, presenting a significant opportunity for budget-conscious shoppers.
- Inventory Drives Stability: With 34 listings, Dallas, TX not only has the highest prices but also the most inventory, suggesting a stable market environment.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Dallas, TX | 34 | $47,288 |
| Los Angeles, CA | 33 | $39,881 |
| New York, NY | 32 | $36,071 |
| Houston, TX | 30 | $29,995 |
| Philadelphia, PA | 29 | $36,747 |
| Miami, FL | 26 | $38,498 |
Pricing by Trim Packages
Key Insights
- Volume Leader: The 450 4MATIC trim dominates with 174 listings, reflecting its popularity among buyers.
- Premium Spread: The AMG CLS 53 4MATIC trim has the highest MSRP at $81,550, indicating a premium segment that may attract performance-focused buyers.
- Drivetrain Effect: All trims feature different drivetrains, with the AWD option generally commanding higher prices, as seen with the 450 4MATIC.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 450 4MATIC | 174 | $72,800 | AWD | 3.0L 362 hp I6 |
| 450 RWD | 63 | $70,300 | RWD | 3.0L 362 hp I6 |
| AMG CLS 53 4MATIC | 4 | $81,550 | AWD | 3.0L 429 hp I6 |
Pricing Analysis by Model Year
Key Insights
- New-Car Premium: The 2023 model year shows a starting MSRP of $76,500, with an average price of $52,145, indicating a significant depreciation trend.
- Depreciation Curve: The 2013 model year has the steepest depreciation at -79.6%, highlighting the rapid loss of value for older models.
- Best Value Sweet Spot: The 2020 model year offers a compelling average price of $33,479, making it an attractive option for buyers seeking value without sacrificing modern features.
Model Year Pricing
| Model Year | Starting MSRP | Avg Price | Avg Price vs Starting MSRP |
|---|---|---|---|
| 2023 | $76,500 | $52,145 | -31.8% |
| 2022 | $72,950 | $48,007 | -34.2% |
| 2021 | $70,300 | $38,926 | -44.6% |
| 2020 | $69,950 | $33,479 | -52.1% |
| 2019 | $69,200 | $31,370 | -54.7% |
| 2018 | $75,150 | $26,442 | -64.8% |
| 2017 | $67,550 | $31,409 | -53.5% |
| 2016 | $66,900 | $22,146 | -66.9% |
| 2015 | $65,990 | $21,071 | -68.1% |
| 2014 | $72,100 | $17,674 | -75.5% |
| 2013 | $72,000 | $14,667 | -79.6% |
| 2012 | $71,300 | $18,027 | -74.7% |
These recommendations are based on CarGurus' proprietary market data from October 21, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
Is the 2021 Mercedes-Benz CLS a good car?
The 2021 Mercedes-Benz CLS sits in a moderate market position, which makes it a reasonable choice if you want a luxury sedan with a balanced mix of availability and deal potential. On the market side, 34.1% of listings are priced as good or great deals, so you do have some room to shop selectively.
That said, the listing pool is not especially large, so you may need to compare condition and pricing carefully rather than waiting for a perfect match. If you find one with strong history and the right equipment, it can be a solid buy.
What should I look for when buying a used 2021 Mercedes-Benz CLS?
At 70.7% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
You should start with a vehicle history report and confirm whether any reported damage was minor or more serious. Put a pre-purchase inspection at the top of your checklist, especially if the car has incomplete records or visible cosmetic inconsistencies. Focus on overall condition, maintenance documentation, and how closely the asking price matches the car’s history.
Is now a good time to buy a used 2021 Mercedes-Benz CLS?
This looks like a moderate, selective buyer’s market, so you can shop with some leverage if you’re patient and compare listings closely.
- Deal availability: 34.1% of listings are priced as good or great deals.
- Inventory: There are 123 listings available.
- Clean inventory: 70.7% of listings are accident-free.
Should I buy a 2021 Mercedes-Benz CLS or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 34.1% of listings are priced as good or great deals.
- At 70.7% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
The bottom line: The 2021 is a sensible target if you want this body style and are willing to shop carefully for condition and history. If you’re more price-sensitive, it makes sense to compare nearby years and prioritize the best-maintained example rather than focusing only on model year.
How does the 2021 Mercedes-Benz CLS compare to the 2021 Porsche Panamera?
| Spec | 2021 Mercedes-Benz CLS | 2021 Porsche Panamera |
|---|---|---|
| Starting MSRP | $70,300 | $87,200 |
| Engine | 3.0L 362 hp I6 | 2.9L 325 hp V6 |
| Horsepower | 362 hp @ 5500 rpm | 325 hp @ 5400 rpm |
| MPG/MPGe (city) | 23 | 18 |
| MPG/MPGe (highway) | 30 | 24 |
| Listings available | 123 | 182 |
| Good & great deal share | 34.1% | 31.9% |
| Accident-free share | 70.7% | 81.3% |
These recommendations are based on CarGurus' proprietary market data from October 21, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
